SCINTOMICS´ spectrum of Quality Control equipment for radiopharmacy LABS

Radio-High Performance Liquid Chromatography (R-HPLC)
Gas Chromatography (GC)
Radio-Thin Layer Chromatography (R-TLC)




High-end performance and powerful features in combination with an exceptional cost/performance ratio.

  • Encapsulated optics design to protect the optical components from fine dust or harmful gases, providing high detection sensitivity and a very stable baseline.
  • Seya-Namioka monochromator and a new blazed holographic concave grating enhance light intensity, ensuring high sensitivity over the entire wavelength range.
  • Automatic compressibility compensation ensures highly precise flow rates.
  • Automatic seal rinsing for improved longevity.
  • Optional vacuum degasser for complete removal of dissolved gases and air bubbles.
  • Column compartment with Peltier elements for accurate temperature control (4°C up to 90°C) and high retention time reproducibility.
  • Integrated tray to safely house solvent bottles.



1.  SCI8112 Isocratic Pump

Parallel dual-plunger pump
Easily upgraded to SCI8110 Quaternary pump


2. SCI8110 Quaternary Pump

Operating principle: Parallel dual-plunger pump, Low-pressure Gradient
Number of Solvents: up to 4
Gradient formation: 4-channel mixing valve
Composition Precision: < 0.1 %
Composition Accuracy: < 0.5 %


3. SCI8111 Binary Pump

Operating principle: Double Parallel dual-plunger pump, High-pressure Gradient
Number of Solvents: 2



1. SCI8160 PDA Detector


Slit Bandwidth:            1.7 nm
No. of PDA channels:   1024
Pixel Resolution:          0.9 nm
Wavelength:                 190~950 nm

Analytical Cell Semi-prep. Cell
Path-length: 10 mm Path-length: 3 mm
Pressure: < 1,500 psi Pressure: < 1,500 psi
Volume: 13 µl Volume: 5 µl
Noise Level: < ± 2•10-5 AU (empty cell, 1 sec Rise Time, 254 nm)
Drift: < 2•10-4 AU/hr (baseline correction), 0.001AU/hr (room temp)
Wavelength accuracy: < 1 nm (HY-1 Holmium Oxide Filter)
GLP Compliance: Photometric Accuracy, Linearity, Noise Level, Drift
System Check


2. SCI8120 UV/Vis Detector

Wavelength Range: 190-900 nm
Data collection rate: up to 50Hz
Light Source: Deuterium & Tungsten Lamp
Noise level: < ±0.35•10-5 AU, 254 nm, dry cell
Drift: < 1•10-4 AU/hr
Bandwidth: 5 nm
Wavelength Accuracy: ±1 nm
Wavelength Precision: ±0.1 nm
Linearity: >99.5 % for 2.5 AU (acetone, 254 nm)
Path length: 10 mm (analytical cell), 3 mm (semi-prep cell)
Cell Volume: 10 µl (analytical cell), 5 µl (semi-prep cell)


3. SCI8170 Refractive Index Detector

RI Range: 1.00 ~ 1.75 RIU
Noise: ≦ 5•10-9 RIU (analytical), ≦ 10•10-8 RIU (semi-prep)
Flow cell vol: 9 µl (analytical), 7 µl (semi-prep)
Cell pressure: 6 kg/cm2 (5.8 bar, 84 psi)
RS232 Control

Further Options:


1. SCI8101 Vacuum Degasser

Number of channel: 4 Channels
Maximum flow rate: 10 ml/min per channel, > 0…2.0 ml/min per channel for removal of 70 % gas from Methanol
Internal volume per channel: 925 µl
Materials in contact with solvent: Teflon and PEEK


2. SCI8131 Column Compartment

Temperature range: 4 °C (Cooling) – 90 °C
Temperature stability: ±0.05 °C
Temperature accuracy: ±0.5 °C
Temperature programs: 40 Steps
Column capacity: Analytical : max. 3 ea of 30 cm column (max. OD 18 mm)
Semi-prep : Max. 2 ea of 30 cm column
Heat-up time: 16 minutes from 4 °C to 80 °C
Cool-down time: 13 minutes from 80 °C to 4 °C
Column switching: max. two automatic 6-port valve (optional)


3. SCI8150 Autosampler

A high-throughput autosampler with state of the art injection technology, fast injection and wash cycles, and an optional Peltier chiller/heater for samples. Full or partial loop injection along with Pressure-Assisted-Sample-Aspiration (PASATM) is possible. The highly efficient needle and internal capillary wash virtually eliminates sample carry-over. Cycle time, including wash, is less than one minute. 96 standard 2 ml vials (32 mm x 12 mm) or well plates (96 or 384 capacity, deep or shallow) can be used.
Sample capacity: Analytical : 2 micro well plates according to SBS standards
Semi-prep : 24 vials of 10 ml (LSV)
Loop volume: 1 – 9999 µl programmable
Reproducibility: RSD ≦ 0.3 % for full loop injections
RSD ≦ 0.5 % for partial loopfill injections
RSD ≦ 1.0 % for µl pickup injections
Carry-over: < 0.05 %
RS232 Control
Cooling/Heating option: 4 °C ~ 40 °C

SCI41000: “Azura” with Mobile Control™:


An “as easy as a smartphone” operable HPLC system.


  • With Azura Mobile Control™ SW – the intuitive user interface that runs on mobile devices.
  • Your daily routine – just a click, always ready, always right.
  • expandable, e.g. auto sampler).
  • analytical gradient HPLC system that needs very little bench space.
  • UV/VIS detector with variable wavelength.
  • pump unit with pressure sensor for a low pulsation eluent supply.


The AZURA Compact HPLC system is based on the multifunctional element ASM 2.1L. This element integrates up to 3 modules in one functional and space-saving unit, e.g.

  • a degasser for a smooth baseline
  • a precise isocratic pump with low pulsation
  • a variable UV wavelength detector


Further deliverables include:

  • Leakage protection
  • Complete software package
  • Notebook
  • Capillary scheme
  • Application note
  • Introduction to operation of software and hardware via short movies

The system is supported by the software package Clarity™ and can also be controlled directly via the intuitive Mobile Control™ Software on a touch screen.
The Mobile Control™ is an intuitive, simple and cost-effective software solution for controlling and monitoring your AZURA Compact HPLC system.
The user friendly system overview provides instant insight into device and system status and allows you to adjust key parameters with your fingertips. The smart user management makes the Mobile Control safe; ensuring that device parameters only be changed by authorized operators.
The graphical display of GLP data helps you avoid problems and unexpected downtime as well as to plan maintenance controls.
With the hand-held Mobile Control (optional) you can check your system remotely, allowing you to oversee multiple systems from the comfort of your office. Alternatively, you can install the Mobile Control directly on your PC.


Ultimate flexibility:

Choose from a variety of integratable modules:

  • Pump with pressure transducer
  • Pump without pressure transducer
  • Degasser 2-channel or 4-channel
  • UV/VIS detector
  • Valve drives
  • VICI Valco valve drives
  • Manual injection valve

Technical  Data

Integrated modules:
UV/VIS Detector UVD 2.1S, Pump P 4.1S with 10 ml pump head, stainless steel
Leak management: Yes
Leak sensor: Yes
Display: 10″ touch screen integrated in Mobile Control
Control: digital: LAN; start, error;
analog out: error; integrator output (+– 2.5 V);

Solvent delivery: Flow rate range 0.01 – 10 ml/min; 0.01 ml/min increments
Max. delivery pressure: 400 bar
Flow rate accuracy: ± 1%, measured at 5 – 50% of flow range using ethanol/water 10:90
Flow rate precision: < 0.5% RSD
Detection wavelength range: 190 – 500 nm
Detection channels: 1
Data acquisition rate: 50 Hz
Light source: D2
Flow cell: without
Spectral bandwidth: Δλ 13 nm
Wavelength accuracy: ± 3 nm
Noise: 30 μAU
Drift: 300 μAU/h
Sensitivity: 6 x 10-5 AU at 1 Hz

Site requirements

The AZURA Compact HPLC System is one of the smallest HPLC systems on the market and needs very little lab space.
Ambient conditions: 10-40 °C, 10-90 % humidity, non-condensing
Dimensions: 361 x 158.2 x 523 mm³ (W x H x D)
Power supply: 100 – 240V; 50 – 60 Hz; maximum 100 W

Compact preparative HPLC for SCINTOMICS GRP modules



Compact-HPLC devices with modern technology and impressive performance, directly controllable by Scintomics Control Center (SCC) Software and GRP User Interface. The ideal partners for GRP-modules.

The system contains the following:


  • a degasser for a smooth baseline
  • a precise double piston pump
  • a variable UV wavelength detector
  • a stainless steel injection valve

Technical  Data


Wavelength range: 190 – 500 nm
Deuterium (D2) lamp with integrated GLP chip
Noise: ± 2.0 • 10-5 AU at 254 nm
Drift: 3.0 • 10-4 AU/h at 254 nm
Linearity: > 2.0 AU at 270 nm
Input 100 – 240 V, output 24 V DC, 60 W
121 x 129 x 187 mm3 (W x H x D), 1.5 kg


Double-piston PUMP P4.1S
Integrated pressure sensor
0.1 – 10 ml/min or 0.1 – 50 ml/min, ceramic/stainless steel
Max. pressure: 400 bar (#1), 150 bar (#2)
Flow rate accuracy: deviation ±1.0%, measured at
5 – 50% of flow range using ethanol/water 10:90
Precision: 0.5% RSD (1 ml/min ,12 MPa), measured at
1 ml/min using ethanol/water 10:90
113 x 135 x 225 mm3 (W x H x D), 2.4 kg


Injection Valve V2.1S 6-Port/2-positions
Stainless steel, Valcon E3, 1/16” capillary connection
105 x 100 x 185 mm3 (W x H x D), 1.9 kg, both without valve
External DC 24V, 60 W


Degasser DG 2.1S 2 channels
Gas permeation through fluoropolymer membrane, max 10 ml/min
Dead volume approx. 285 μl per channel
Maximum pressure stability 7 bar
Wetted materials PEEK, glass-filled PTFE, Teflon AF®
121 x 138 x 190 mm3 (W x H x D), 2,3 kg, 85 – 265 V, 50 – 60 Hz, 20 W

Site requirements


The compact HPLC prep system is one of the smallest HPLC systems on the market and needs very little lab space.


Ambient conditions:
10-40 °C, 10-90 % humidity, non-condensing


Dimensions of components:
UV detector: 121 x 129 x 187 mm³ (W x H x D)
Double Piston pump: 113 x 135 x 225 mm³ (W x H x D)
Injection valve: 105 x 100 x 185 mm³ (W x H x D)
Degasser: 121 x 138 x 190 mm³ (W x H x D)


Power supply:
100 – 240V; 50 – 60 Hz; maximum 100 W


SCINTOMICS SCI5500 Gas Chromatography (GC) System:

a new member of the powerful family of Scintomics’ QC instruments dedicated to radiopharmacies.


The SCI5500 Gas Chromatograph is a rectangular box, approximately 605 mm width, 455 mm height, 550 mm depth. The weight is 55 kg. It has a control panel for operation on the right side.

The control panel has a LCD screen for input of the operating conditions and display of the input data, a LED for display of the status of the equipment, and a keypad for operation of the equipment and input of variables. There is a power button below the control panel and a column oven on the left side of it. The oven opens by pushing a button which is below it.


The inlet is on the left side of the equipment. It can be connected with the auto sampler. The detectors are on the right-upper side. You can install each three inlets and detectors and four valves to handle gas samples. You can also set the volume of gas by using the Advanced Pneumatic Control (APC) system which is connected with the inlets and detectors. The APC is on the right side at the back of the Equipment.

Technical Data

Gas Chromatograph SCI5500 GC Oven System Module
Usable volume: 14 l
Automatic cooling under processor control
Temperature operating range: ambient to 450℃ or more
-80℃ ~ 450℃ (with LN2 cryogenic cooling)
-55℃ ~ 450℃ (with LCO2 cryogenic cooling)
Temperature set-point Resolution: 1℃
Programming: 25 ramps, 26 steps temperature program
Maximum set-point heating rate: 100℃/min
Run time: Maximum 9,999 min
Cool down rate: 6.5 minutes from 450℃ to 50℃
Temperature program methods: Maximum up to 20
Temperature stability: ±0.01℃ (Isothermal), ±0.1℃ (Gradient)
Improved column conditioning function: Automatic set of split flow up to 5 ml/min on column conditioning
Prevention of oven malfunction (Over heating)
Heated Devices: 10 heated zones Standard
Injector (Maximum no. of inlet installations: three)
Packed inlet
Maximum Temperature: 450 °C
Pressure setting range: 0.01 ~ 100 psi
Total flow setting range: 0.1~100 ml/min
Flow stability: < ±0.05ml/min
Pressure stability: < ± 0.05psi
Temperature setpoint: 1℃
Temperature stability: < ±0.1℃

Capillary inlet (Split/Splitless)
Maximum Temperature: 400 °C
Pressure setting range: 0.01 ~ 100 ml/min
Total flow setting range: 0.1 ~ 400 ml/min N2 , 0 ~ 1000 ml/min He
Splitless time setpoint: 0.01min
Total Flow stability: < ±0.05 ml/min
Pressure stability: < ± 0.05 psi
Temperature setpoint: 1℃
Temperature stability: < ±0.1℃

On-column inlet
Maximum Temperature: 450 °C
Pressure setting range: 0.01 ~ 100 psi
Total flow setting range: 0.1 ~ 100 ml/min
Flow stability: < ±0.05 ml/min
Pressure stability < ± 0.05psi
Temperature setpoint: 1℃
Temperature stability: < ±0.1℃
Temperature programming: up to 5 steps

Advanced Pneumatic Control (APC)
Up to 6 APC blocks for inlets, detectors or auxiliary gases
Increased precision and accuracy in pressure and flow rate
-> Increased sampling rate for flow and pressure
-> Increased frequency of valve Controlling
-> Shockproof APCs
-> Automatic compensation for temperature & pressure in installation condition
Up to 6 APCs can be installed and up to 18 channels of APC
Flow set-point: 0.1ml/min
Pressure set-point: 0.01psi
All gas flows controlled by APC
Available gases: N2, He, H2, Air, Ar/CH4
Constant flow, Constant pressure
Programmed flow: 5 steps, Programmed pressure: 5 steps
Leak detection: after an alarm for a shortage of gas, it automatically saves the method and shuts down
Gas saver

Maximum no. of detectors to be installed: 3
Data acquisition rate: 200 Hz

Flame Ionization Detector (FID)
Maximum operating temperature: 450°C
Automatic flame ignition
Temperature set-point : 1 ℃
Ignition message: Alarm message as ‘Flame out’
MDL: 2.0 pg carbon/sec
Linear dynamic range: 107
Temperature stability: ± 0.1℃
Air: 0~500 ml/min
H2: 0~100 ml/min
Make-up gas: 0~100 ml/min

Thermal Conductivity Detector (TCD)
Maximum operating temperature: 400 °C
Flow through cell: 4 Rhenium-Tungsten filaments
MDL: 2.5 ng/ml (Standard), 400 pg/ml (µTCD)
Filament protection
Temperature set-point: 1 ℃
Micro-cell (option)
Ref: 0~100 ml/min
Make-up: 0~100 ml/min

Nitrogen-Phosphorous Detector (NPD)
Maximum operating temperature: 400 °C
MDL: <0.4 pg N/sec (Azobenzene), <0.2 pg P/sec (Malathion)
Dynamic Range for N: > 104
Dynamic Range for P: > 104

Flame Photometric Detector (FPD)
Maximum operating temperature: 300 °C
Minimum detection limit for S: < 20 pg S/sec
Minimum detection limit for P: < 0.5 pg P/sec
Dynamic Range for S: > 103
Dynamic Range for P: > 104
S/C Selectivity: 105
P/C Selectivity: 106

Pulsed Discharge Detector (PDD)
Maximum operating temperature: 400 °C
PDHID, PDECD mode is selectable
APC not supported
Helium ionization mode(PDHID): Linearity 105
MDL (organic compound: low ppb), (permanent gas: low ppm)
Electron capture mode (PDECD): Linearity 105
MDL – 10-15
Dopant gas: 3% Xe in Helium

Electron Capture Detector (ECD)
Maximum Operating Temperature: 400 ℃
Minimum Detection Limit for S: 10 fg/sec
Linear Dynamic Range: > 104

Site Requirements

Electricity: 230 VAC 60Hz, 16A

Size: 605 mm x 455 mm x 550 mm (WxHXD)

Weight: 55 kg

A new Radio-Thin Layer Chromatography (R-TLC) system from SCINTOMICS is coming soon! Please stay tuned!

SCINTOMICS BSI* γ-Spectrometer:


The easy to install and operate solution for all your isotope characterization needs – powered by USB.

Gamma spectrometer based on NaI(Tl) detector, incl. SpectraLineGP™ software package, USB cable and documentation.

  • Entirely powered from USB Interface
  • Low power consumption
  • Well suited for laptop Operation
  • Small size, compact housing
  • Only one cable required for Operation
  • High Integration
  • Useable with many application program

*The spectrometer is a product of Baltic Scientific Instruments, Riga, Latvia



The SCINTOMICS BSI Gamma Spectrometer combines a 51 mm x 51 mm NaI(TI) well-type crystal, a photomultiplier tube, a high voltage power supply, a preamplifier and a MCA527 micro multi-channel analyzer module within one rugged housing. The whole system is entirely powered from the USB interface. Due to the integration of all hardware components required for a gamma spectroscopy system in one package, only one USB cable is required to connect the detector to a computer. This simplifies the usage and lowers the total costs of the gamma spectrometer.
The gamma spectrometer is operated with the SpectraLineGP™ software package. The only requirement is that the host computer has an integrated USB high power hub or host port.

Lead shield
Alternative Crystal Sizes:
51 mm x 51 mm (2″ x 2″)
63 mm x 63 mm (2.5″ x 2.5″)
76 mm x 76 mm (3″ x 3″)

SpectraLine GP™ software
Gamma Precision (GP)™ software has been developed for precision spectrometric measurements and processing of γ-spectra, measured by semiconductor and scintillation spectrometers.

Main Features

  • Automatic peak search
  • Calibration by energy, half-width, and peak shape
  • Calculation of peak parameters
  • Calibration by efficiency
  • Activity calculation
  • Correction for true summation
  • Simultaneous processing of multiple spectra
  • Quantitative and visual control of the calibration quality
  • Connection of an arbitrary number of measurement channels
  • Independent control, start, stop, spectra storage in all channels
  • Color scheme adjustment of the window
  • Data copying into the spectrum Windows
  • Addition/deletion of peaks and zones in a spectrum
  • Viewing parameters of indicated zones or separate peaks
  • Zone integration or splitting into smaller zones
  • Viewing of calibration results, corrections, calculations, etc.
  • Creation of libraries of task specific configurations
  • Information is provided on the radionuclide designation, its half-life, line energy, line intensity, and absolute error.
  • Built-in editor, allowing to create reports of various forms and to connect to external programs.

Supported data formats:

*.spc (SPC “Aspect”) *.chn (Ortec)
*.mca (BSI, XIA) *.cnf (Canberra)
*.wsp *.asc (IAEA)
*.ats (Atomtex) *.spm (extended, “LSRM”)

Technical Data


Crystal Size: 51 mm x 51 mm

Energy Resolution (FWHM @ 662keV): 6.2% typ. / 7% max
Energy Range: 20 keV to 3 MeV
Number of Channels; 128, 256, 512, 1024, 2048
Digital Filter: adjustable
Maximum Throughput: > 100,000 cps
Special Features: integrated temp. sensor, Multi-Channel Analyzer
Computer Interface: USB2.0, Micro-B Receptacle
Power: entirely powered from USB
Power Consumption (typical): < 1W (Idle / Measurement)
Detector Dimensions: 83.5 mm x 296 mm
Operating Temperature Range: 0°C to 40°C
Detector Weight: 1350 g

Site requirements


Space requirement (with shielding):
500 x 570 x 500 mm³ (width x height x depth)
Ambient conditions:
0-40 °C, 20-80 % relative humidity, non-condensing
Power supply:
110 – 240 V AC ± 10%, 50/60 Hz (for PC)
Total weight (shield & detector):
~ 150 kg